Visceral Leishmaniasis: New Health Tools Are Needed

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Visceral Leishmaniasis: New Health Tools Are Needed

0590 V isceral leishmaniasis (VL), commonly known as kala-azar, from the Hindu vernacular, is a human systemic disease caused by parasitic protozoan species of the genus Leishmania. Transmitted by the bite of the tiny and seemingly innocuous female phlebotomine sandfl y (Figure 1), the parasite enters macrophages, where it multiplies and establishes the infection (Figure 2). A multitude of clin...

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Visceral leishmaniasis in the New World & Africa.

Visceral leishmaniasis in the New World, primarily found in northeastern Brazil, is caused by Leishmania chagasi. Compared to India, unusual features of Brazilian disease are the large number of asymptomatic infections versus symptomatic infections, and the apparent change from a zoonotic disease to a partially anthroponotic one. Visceral disease in Africa is caused by L. donovani as in India, ...

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Visceral leishmaniasis.

While fully agreeing with Mr Cudmore that orchidopexy at 2 years of age is a difficult procedure and that the majority of orchidopexies are carried out by general surgeons or, unfortunately, delegated to a junior member of the team, the clinical and experimental evidence supporting orchidopexy at around the age of 2 years is overwhelming. The optimal age for orchidopexy cited in the annotation ...

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Visceral leishmaniasis in children

Background and Objectives: Visceral leishmaniasis is a chronic disease in Africa and Asia, children under 5 years are affecting with L.infantum and older children and young adult with L.donovani Purpose of this study describes the characteristics of epidemiologic and clinicopathophysiologic and response to treatment of patient that affected in East Azarbaijan compared with other endemic areas ...

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Visceral leishmaniasis.

Visceral leishmaniasis (VL) is a vector-borne parasitic disease targeting tissue macrophages. It is among the most neglected infectious diseases. Classical manifestations of VL include chronic fever, hepatosplenomegaly, and pancytopenia. Most cases can be detected through serologic and molecular testing. Although therapy has historically relied on antimonials, newer therapeutic options include ...

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ژورنال

عنوان ژورنال: PLoS Medicine

سال: 2005

ISSN: 1549-1676

DOI: 10.1371/journal.pmed.0020211